Mutational signatures in cancer interplay of DNA damage and repair
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Learning More About Changes in Cancer Cell Identity | Genetics And Genomics
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2018年8月8日
broadinstitute.org
Cancer progression is often driven by state, not just cell type. The most aggressive cancer cells tend to have stem-like features and high plasticity. This means they can rapidly adapt, change identity, and regenerate, which allows them to spread quickly and evade treatment. These adaptable cells consume high energy, shift their profiles to hide from detection, and are especially difficult to target unless something makes them visible, as seen in some cases like melanoma. Across breast, gastric,
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Cancer progression is often driven by state, not just cell type. The mo…
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genome.gov
16K views · 215 reactions | 六‍ New research from our teams at Cambridge shows why certain blood DNA mutations don’t appear until later in life. It's an important piece of the puzzle to understand how blood cancers develop with age, and raises hope that one day we may be able to prevent or delay them. Learn more about these findings and what they could mean for the future treatment  https://bit.ly/47TszY7 | Blood Cancer UK | Facebook
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16K views · 215 reactions | 六‍ New research from our teams at Cambr…
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