The functions of biomolecules, including lipids, nucleic acids and especially proteins are determined to a great extent by their structure. This structure–function relationship is a foundation of many ...

The protein homeostasis (proteostasis) network (Balch et al, 2008), consisting of a collection of molecular chaperones, ...

In a recent study published in the journal Nature, a large team of researchers from the United States (U.S.) used single-cell ribonucleic acid (RNA) sequencing combined with high-resolution ...

A new discovery inside your cells may change how scientists understand disease and design future treatments. Researchers have ...

Late-onset Alzheimer's disease (LOAD) is the most common form of dementia, with symptoms appearing after age 65. Since carriers of clusterin risk alleles have an increased likelihood of developing ...

Investigators have created computer-generated models to bridge the gap between 'test tube' data about neurons and the function of those cells in the living brain. Their study could help in the ...

Home > Pressemitteilung: Structure of clusterin decoded: New ...

Per- and polyfluoroalkyl substances (PFAS), manmade chemicals that accumulate in the body over time, have been linked to liver disease and cancer, but it is not yet clear how they cause damage.

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists ...