Sign up for CNN’s Wonder Theory science newsletter. Explore the universe with news on fascinating discoveries, scientific advancements and more. The United Kingdom ...

When the genome-editing tool CRISPR is thought of as a potential medicine, the targets that first come to mind are diseases like sickle cell or other conditions caused by particular mutations. Use ...

本研究针对传统CRISPR-Cas系统挖掘方法的局限性，创新性地采用进化尺度语言模型（ESM）开发了AIL-Scan策略，成功鉴定了7种未记录的Cas12a亚型。通过整合机器学习与结构生物学技术，揭示了这些亚型独特的PAM识别特性和核酸酶活性，首次实现了无需传统PAM序列的 ...

The practice of genetic modification is as old as humanity. For thousands of years, humans have bred crops, livestock and even pets that possess desirable traits. This selective process, which alters ...

With such striking effects, many scientists see modulating the microbiomes as a promising avenue for improving human health and wellbeing. In recent years, researchers have shown that tweaking the ...

本研究通过全基因组CRISPR/Cas9筛选发现组蛋白甲基转移酶SUV39H2是口腔鳞癌(OSCC)抵抗溶瘤病毒oHSV-1的关键因子。研究人员证实 ...

CRISPR technology has revolutionized genetic testing and disease detection, offering precise, rapid, and cost-effective diagnostic solutions. This gene-editing tool has been adapted for molecular ...

CRISPR's business needs consistent revenue that could come from its gene-editing therapy exa-cel. Investors shouldn't expect profitability anytime soon, however, as the company's losses are deep and ...