Long non-coding RNAs exist in the so-called "Wild West" (99%) of the human genome that is currently understudied. Not only does this finding have treatment implications for patients with ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

The expression of genes has to be very carefully controlled by cells; serious problems can arise when genes are expressed in the wrong places, at the wrong times, or at the wrong levels, for some ...

Impact of variant allele frequency (VAF) of TP53 alterations and Signatera circulating tumor DNA (ctDNA) monitoring for patients (pts) with advanced urothelial carcinoma (aUC) treated with enfortumab ...

Retinitis pigmentosa (RP) is a genetic eye disorder affecting around one in 5,000 people worldwide. It typically begins with night blindness in youth and progresses to tunnel vision as ...

Researchers from Proqr Therapeutics NV recently presented preclinical data on AX-0810, a single-stranded RNA editing oligonucleotide (EON) targeting RNA coding for NTCP cotransporter ...

RNA，作为细胞信号传导的重要使者，在许多疾病中扮演着重要的角色，无论是神经退行性疾病还是衰老，都有研究者在开发相应的RNA疗法。 西湖大学讲席教授付向东自1992年建实验室时起，就一直在做RNA方面的基础研究和转化应用。他于2010年入选美国科学促进会 ...

Although the participation of spliceosomes is almost always required for intron removal, a few types of genes have self-splicing RNA introns.

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to ...

The discovery of a juvenile woolly mammoth named Yuka, found in Siberian permafrost with its skin and muscles intact, has already marked paleontological history. A team of scientists has just added an ...