Chemical synthesis and peptide ligation techniques have revolutionised the field of protein engineering by enabling the precise construction of peptides and proteins with tailored modifications. These ...

A major problem in solid-phase peptide synthesis (SPPS) is aggregation and poor solvation leading to incomplete deprotection and/or coupling steps, resulting in low crude purity peptides. 1 This ...

There has been a recent revival in interest in peptide therapeutic development, with five of the top-selling drugs being peptides or proteins (Enbrel, Remicade, Humira, Avastin, MabThera) and many ...

Small-molecule drugs have been instrumental in alleviating a gamut of ailments, from heart disease to the humble headache, but some experts now think we’ve exhausted the number of targets those drugs ...