A groundbreaking new book – the first of its kind in Chinese – is now available to empower researchers with the powerful tool of Mendelian randomization. Translated from the esteemed text "Mendelian ...

Traditional epidemiological studies have identified numerous potential risk factors, but observational studies have struggled to establish causal links due to confounding factors and reverse causation ...

By Tarun Sai Lomte A large genetic analysis suggests that one amino acid linked to protein metabolism could influence how ...

Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including ...

Metabolic dysfunction, rather than steatotic liver disease (SLD), seems to be the main driver of chronic kidney disease (CKD) risk.

Using MR-SPI and AlphaFold3, scientists unravel the molecular underpinnings of Alzheimer’s disease, identifying key protein changes that could reshape future treatments. Study: Deciphering proteins in ...

A higher body mass index (BMI) appears to be causally related to a greater risk for vascular-related dementia.