Chromosome 11 consists of approximately 144 Mb of DNA [1], representing around 5% of the human genome. Meiotic linkage analysis suggests a sex-averaged genetic map of approximately 162 cM [2]. The ...

Cancer develops via multiple, cumulative steps, many of which precede the development of clinically and even microscopically recognizable disease. Mapping and human genome sequence analysis of ...

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...